Product Description
Age-related cognitive decline can impact what you understand, process, and remember. That’s why we developed newly reformulated Cognitex® Elite: to provide the brain-friendly nutrients you need to support and maintain cognitive function and health at any age!
Benefits at a Glance:
- Now contains unique SIBELIUS™: SAGE extract
- Promotes rapid improvements in attention and focus1
- Encourages healthy mood and memory1
- Supports brain blood circulation and neurotransmitter balance2-4
- Helps inhibit inflammation in the brain7,8
More facts about Cognitex® Elite
A healthy adult brain has about 100 billion nerve cells, and each one needs specific nutrients in order to perform optimally. Our Cognitex® formulas provide a steady supply of specially selected nutrients clinically shown to support brain health as you age.
SIBELIUS™: SAGE extract for attention and memory
Sage extract helps promote healthy levels of the essential neurotransmitter acetylcholine.9 In a double-blind placebo-controlled study in young healthy adults, sage extract promoted healthy mood and cognitive performance.10 Our Cognitex® Elite formula uses SIBELIUS™: SAGE — a unique sage extract with distinct health benefits not seen with other sage extracts. It also helps modulate healthy signaling of neurotransmitters like GABA, dopamine, serotonin, and more.
In a randomized, placebo-controlled, double-blind clinical study in healthy older adults, 333 mg of SIBELIUS™: SAGE quickly improved accuracy of attention scores compared to a placebo after only 1 hour.1 This proprietary sage extract also rapidly encourages secondary (long-term) memory and promotes healthy blood flow within the brain.10 And in pre-clinical studies, it promoted healthy expression of genes involved in lipid metabolism and insulin signaling pathways.11
Vinpocetine supports brain health
Derived from the periwinkle plant, vinpocetine inhibits the phosphodiesterase type-1 enzyme to promote cognitive function.12-14 Vinpocetine supports healthy inflammatory response as well.6,7 It also enhances cerebral metabolism by helping maintain healthy blood flow and support oxygen and nutrient delivery to brain cells.2-4
Enhance brain function with AuroraBlue®
Blueberry phytonutrients can help inhibit age-related decline in cognitive and motor function.15,16 Wild blueberry extracts have been shown to inhibit oxidative and inflammatory factors in brain cells believed to affect memory health.17,18
Our formula uses AuroraBlue®, a whole-food complex of various blueberry species from pristine Alaskan tundra with powerful antioxidant properties.
Phosphatidylserine supports brain cellular structure and function
Phosphatidylserine (PS), an essential component of healthy cell membranes, is critical to brain metabolism and function, and supports brain-cell-to-brain-cell connections.5,19 Phosphatidylserine (PS) promotes healthy cognitive function, healthy memory, concentration, attention, and more.20-25 Additionally, PS helps the brain use its fuel efficiently by facilitating glucose metabolism and stimulating production of acetylcholine, a key neurotransmitter.26-28
Ashwagandha provides neuroprotective and brain-calming effects
Ashwagandha provides neuroprotective effects by promoting the healthy growth of axons and dendrites, nerve cell components that support brain and nervous system function.29-31 Ashwagandha also has beneficial effects on mood,32 and helps the body to adapt to stress33 to promote well-being. It inhibits an enzyme that breaks down acetylcholine, which helps to maintain youthful cognition and memory.34
Uridine-5'-Monophosphate supports healthy brain function
In pre-clinical studies, Uridine-5’-Monophosphate (UMP) has been shown to promote healthy levels of neurotransmitters acetylcholine and dopamine, which supports healthy brain function.35,36
PLEASE NOTE: This formula is also available with pregnenolone.
These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Supplement Facts | ||||||||||||||||||||||
Non-GMO SIBELIUS™ is a trademark of Sibelius Limited and used under license. |
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Dosage and Use | ||||||||||||||||||||||
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Caution | ||||||||||||||||||||||
If you are taking anticoagulant or antiplatelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product. |
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Warnings
To report a serious adverse event or obtain product information, contact 1-866-280-2852. |
Reference:
- http://www.alz.org/documents_custom/report_alzfactsfigures2010.pdf. Accessed July 10, 2015.
- http://www.ninds.nih.gov/disorders/neurotoxicity/neurotoxicity.htm. Accessed August 16, 2013.
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- Dialogues Clin Neurosci. 2013 Mar;15(1):67-76.
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- J Pharm Pharmacol. 1997 Nov;49(11):1162-4.
- J Tradit Chin Med. 1997 Dec;17(4):299-303.
- Fundam Clin Pharmacol. 2015 Aug;29(4):371-81.
- Neurosci Lett. 2015 May 6;594:40-5.
- Biochim Biophys Acta. 2013 Mar;1831(3):523-32.
- Food Chem Toxicol. 2011 Jun;49(6):1303-15.
- Ann N Y Acad Sci. 1994 Jun 30;717:253-69.
- J Int Med Res. 1991 Jul-Aug;19(4):330-41.
- J Neurol Sci. 2011 Jun 15;305(1-2):34-7.
- Curr Biol. 2015 Jun 1;25(11):1461-8.
- Ideggyogy Sz. 2007 Jul 30;60(7-8):301-10.
- Phytomedicine. 2009 Mar;16(2-3):111-7.
- J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5.
- Psychopharmacology (Berl). 2014 Sep;231(17):3537-56.
- Biosci Biotechnol Biochem. 2007 Sep;71(9):2223-32.
- J Agric Food Chem. 2011 Apr 27;59(8):3674-85.
- J Periodontol. 2008 Jan;79(1):174-80.
- J Cell Biochem. 2010 Dec 1;111(5):1270-9.
- Mol Nutr Food Res. 2010 Jul;54 Suppl 2:S205-13.
- Mol Nutr Food Res. 2009 Sep;53(9):1143-55.
- Ann NY Acad Sci. 2007 Apr;1100:470-85.
- Phosphatidylserine: Number One Brain Booster. New Canaan, CT: Keats Publishing; 1998.
- Sports Med. 2006;36(8):657-69.
- Altern Med Rev. 2008 Jun;13(2):85-115.
- Eur J Clin Pharmacol. 1992;42(4):385-8.
- Annu Rev Biophys. 2010 Jun 9;39:407-27.
- Nutrition. 2003 Nov-Dec;19(11-12):957-75.
- Neurobiol Aging. 2001 Jan-Feb;22(1):9-15.
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- J Neural Transm Suppl. 1987;24:239-45.
- Isr J Psychiatry Relat Sci. 2000;37(4):302-7.
- Clin Interv Aging. 2010 Nov 2;5:313-6.
- Dement Geriatr Cogn Disord. 2010;29(5):467-74
- Altern Med Rev. 2008 Sep;13(3):245-7.
- Br J Pharmacol. 2005 Apr;144(7):961-71.
- Eur J Neurosci. 2006 Mar;23(6):1417-26.
- Yakugaku Zasshi. 2008 Aug;128(8):1159-67.
- Int J Dev Neurosci. 2005 Oct;23(6):501-7.
- Metabolism. 2008 Oct;57 Suppl 2:S6-10.